Pedro M R Reis
Erlangen University, Germany
Posters & Accepted Abstracts: Neurochem Neuropharm
Methodology that would allow the investigation of interactions between brain activity sources, natural motor behavior and drug interactions would bring benefits such as personalized treatments for ADHD and understanding of disease mechanisms. With such methods, investigators and clinicians would be able to monitor and adjust treatments of impairing motor conditions. On one hand, Pharmaco-EEG allows the inspection effects of substances in the central nervous system activity. However, Pharmaco- EEG leaves out the effects on motor behavior and how physical exercise influences pharmacokinetics. On the other hand, electroencephalography suffers from inherited methodological problems that restrict its use during motion. Yet, this is the only light enough mobile non-invasive sensing modality with adequate temporal resolution to record brain activity on the time dimension of natural motor behavior. Recent advances allow for synchronous measurements of brain and body dynamics (MoBi). Combining MoBi methods with pharmacokinetic analysis results in the creation of Pharmaco-Mobile Brain Body Imaging (P-MoBi). Using source localization to determine the cortex areas responsible for different activities, and the time resolution of the EEG for functional connectivity brain mapping, researchers may be able to determine the changes and influences of the resulting interaction between exercise and medicaments on brain functions and corresponding motor performance. This talk presents the research potential of P-MoBi methodologies and innovations that allow such measurements.
Email: pedro.reis@fau.de
