Journal of Neuroscience and Neuropharmacology

Intravenous Pyogenic Granuloma

Intravenous pyogenic granuloma (IVPG) is a particularly rare polypoid variant of lobular capillary hemangioma. It was first described in 1979 by Cooper et al. and a most recent review found less than 30 cases reported in literature until now. IVPG has been seen in patients from 15 to 66 years aged (average 38 years) and with a small female predominance. These lesions are commonly thought to arise in upper extremities and in neck and head veins. IVPG may be a benign intravascular lesion with no potential for haematogenous spread. The proliferation is entirely confined within a vein lumen and a fibrovascular stalk attaches the lesion to the wall of the vein with a close-by small artery thought to provide its blood supply. The surface of the tumor exposed to the vein lumen is roofed by an endothelial lining. Typical histological features include lobules of capillaries within an edematous fibromyxoid stroma.

Relevant Topics in Neuroscience & Psychology