Faculty of Pharmacy, Al Azhar University of Gaza, Gaza Strip, Palestine
Research Article
Effects of Vitamin C Supplementation with and Without Endurance Physical Activity on Calcium and Parathyroid Hormone Levels in Metabolic Syndrome Patients: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Author(s): Abdel Hamid El Bilbeisi*, Amany El Afifi, Halgord Ali M Farag, Mahmoud Taleb, Riad El Qidra and Kurosh Djafarian
Background: This study was conducted to determine the effects of vitamin C supplementation with
and without endurance physical activity on calcium and parathyroid hormone levels in metabolic
syndrome patients.
Methods: In a parallel-randomized, double-blind, placebo-controlled clinical trial, 120 metabolic
syndrome patients, was randomly assigned into four groups. Biochemical tests were assessed as
baseline and after 12 weeks of intervention. Statistical analysis was performed using SPSS version 20.
Findings: A significant decrease in mean serum calcium levels were seen in participants who received
vitamin C or “vitamin C plus 30 minutes/day of physical activity” and “placebo plus 30 minutes/day
of physical activity” (p value<0.001). Furthermore, we observed a significant de.. View More»
