Ching Siew Mooi
Universiti Putra Malaysia, Malaysia
Keynote: Primary Health Care
Gestational Diabetes (GDM) is one of the major public health issues in Asia. The present study aimed to determine the prevalence of and risk factors for GDM in Asia by performing a systematic review and meta-analysis. We systematically searched in PubMed, Ovid, Scopus and ScienceDirect for observational studies in Asia from January 1980 to August 2017. We selected cross-sectional studies reported the prevalence and risk factors for GDM. A random effects model was used to estimate the pooled prevalence of GDM and Odds Ratio (OR) with 95% CI. There are 84 papers out of 296 papers were included in this paper. The pooled prevalence of GDM in Asia was 11.5% (95% CI 10.9-12.1). There was a considerable level of heterogeneity in the prevalence of GDM in Asia and it was probably due to differences in diagnostic criteria, screening methods and study setting. Current meta-analysis of data found that the risk factors of GDM are history of previous GDM (OR 8.24, 95% CI 5.24-12.96), history of malformed baby (OR 5.04, 95% CI 2.02-12.58), history of macrosomia (OR 4.41, 95% CI 3.09-6.31), BMI 25 and above (OR 3.39, 95% CI 2.92-3.93), concurrent PIH (OR 3.20, 95% CI 2.19-4.68), family history of diabetes (OR 2.66, 2.12-3.33), history of still birth (OR 2.39, 95% CI 1.68-3.40), PCOS (OR 2.33, 95% CI1.72- 3.17), history of abortion (OR 2.25, 1.54-3.29), age 25 and above (OR 2.17, 95% CI 1.96-2.41), multigravida 2 and above (OR 1.97, 95% CI 1.34-2.91) and history of preterm delivery (OR 1.93, 95% CI 1.21-3.08). We found a high prevalence of GDM in Asian population. Patients with history of previous GDM and history of malformed baby and history of macrosomia should receive more attention and effective interventions are needed to decrease GDM burden in this continent.
Ching Siew Mooi is an Associate Professor in the Department of Family Medicine at the Universiti Putra Malaysia. She has obtained her Master’s degree in Family Medicine at University of Malaya. Her research interests lie in the area of non-communicable disease like blood pressure, obesity, diabetes and addiction. She has published more than 50 manuscripts in peer review journal at the national and international level.
E-mail: sm_ching@upm.edu.my