Primary Health Care: Open Access

Chronic degenerative lung diseases are recognized as untreatable pathological diseases, significantly affecting both life span and life quality of human-beings. Chronic obstructive pulmonary disease (COPD) presents a group of lung diseases that block the airflow and lead patients difficult to breathe, is predicted to be the third leading cause of death by the end of 2020s according to the World Health Organization. It is also widely established that patients with COPD are at increased risk for the development of primary lung cancer. Based on current medicine and technologies, the only treatment for COPD is lung transplantation, while there is always acute shortage of donor lungs. It has been reported that adult lung has the capacity for both regeneration and regrowth. However, loss of alveolar units and the emerging of pulmonary fibrosis often trigger repeated episodes of injury, thus resulting in unceasing consumptions of endogenous lung repair capacity. his makes the authentic therapeutic lung regeneration still a long-term goal. Recent emerging regenerative medicine has shed a light on the path for finding a new way to treat COPD instead of seeking lung transplantations. Approaches include not only generating new lungs in vitro and replenishing exogenous stem cells to the damaged parts, but also using pharmacologically selection for promoting the healthy cells survival other than damaged ones. All these methods are based on numerous basic researches focusing on lung developmental and regeneration pathways. This information can be published in our peer-reviewed journal with impact factors and are calculated using citations not only from research articles but also review articles (which tend to receive more citations), editorials, letters, meeting abstracts, short communications, and case reports. The inclusion of these publications provides the opportunity for editors and publishers to manipulate the ratio used to calculate the impact factor and try to increase their number rapidly. The impact factor plays a major role in the particular journal. Journal with higher impact factor is considered to be more important than other ones.