Editorial Board, Primary Health Care: Open Access, United Kingdom
Perspective
Exploring the Relationship between Celiac Disease and Gut Microbiota
Author(s): Patricia Laughlin*
Celiac Disease (CD) is a prevalent systemic condition arising from an aberrant immune reaction to gluten consumption, primarily affecting the small intestine. In individuals with a genetic predisposition, CD can be incited by external factors, such as viral infections and disruptions in the gut microbiota, known as dysbiosis. The gut microbiome plays a crucial role in regulating the immune system, and recent discoveries suggest that alterations in the gut microbiome might contribute to various chronic immune disorders, including CD, although the precise mechanisms are still under investigation. Certain bacteria in the gut exhibit epitopes that resemble gliadin, potentially intensifying the host's immune response. Additionally, some bacteria, like Pseudomonas aeruginosa, may collaborate with gluten to initiate and exacerbate intestinal inflammation. The microbiota might also direct.. View More»
DOI:
10.35248/2332 2594.23.13(9).525
