Muhammad Umair Khan, Janati, N. Alghassab and Sofiane Ghorbel
Accepted Abstracts: J Neurol Neurophysiol
Introduction:Isotretinoin is the mainstay therapy for severe and nodulocystic acne. Myalgia and muscle stiffness have been reported in 16-51% of patients treated with isotretinoin , while elevated serum creatine kinase (CK) levels have been found in up to 41% . In this paper, we report, for the first time, the occurrence of pelvic girdle myopathy in a teen who received isotretinoin therapy. Methods: This was a case study conducted at King Khalid Hospital. Results: Histopathology and other laboratory data were consistent with an inflammatory myopathy based on a vasculitic process. Conclusion: Our data indicate that the myopathy caused by isotretinoin is an inflammatory process based on vasculitis, resulting in ischemic muscle necrosis. Biography Muhammad Umair Khan is a 4 th year medical student at Dow University of Health Sciences, Karachi, Pakistan. He is also working as a Research Associate at King Khalid Hospital, Hail, Saudi Arabia.
