Short Communication - (2017) Volume 6, Issue 4
Introduction: Single photon emission computed tomography has been introduced as a promising new diagnostic tool in orthopaedic pathology since the early 90'. Computed tomography, the combined with SPECT, gives insight in the specific sight of wrist pathology. Literature already supports introduction of SPECT/CT in wrist pathology, but clinical application is lagging.
Case Report: A 40yr old patient reported first in 2004 with persisting pain after a right distal radius fracture. Several diagnostics and operative interventions were performed, all unsuccessful. Because of the persisting pain a SPECT-CT was performed which showed a cyst in the hamate bone, which was successfully enucleated. The patient was finally pain free at recent follow-up. With a QDash-score of 43 and a PRW (H) E-DLV-score of 58/150.
Discussion: In this case report, SPECT/CT proved a very sensitive diagnostic tool for specific pathology of the wrist. It offered precise localisation and thereby the clinically suspected diagnosis was confirmed and the patient successfully treated.
Keywords: Proximal row carpectomy; Single-Photon Emission- Computed Tomography; SPECT/CT; Capitate; Hamate; Wrist
Single photon emission computed tomography (SPECT) has been introduced as a promising new diagnostic tool in orthopaedic pathology since the early 90's [1-3]. Dubowitz et al. [4] already concluded that combining scintigraphy and SPECT improved the localization of abnormalities in the wrist, but to distinguish between the carpal bones remained difficult [4].
The need for imaging that would give insight in the exact pathological sight raised. Hirschmann et al. [5] described a new technique of embedding computed tomography, the precise anatomic localization and SPECT, abnormal bone metabolism [4-6].
Could this new technique be able to offer insight in the exact localization of the pathology (Figure 1) in uncomprehend wrist pathology? SPECT/CT is a technique where computed tomography (CT) scan is combined with metabolism and a 3-dimensional image [7,8]. Radiation exposure is only 2-5 mSV [9]. This technique has already been applied into several clinical orthopaedic pictures; femoro acetabular impingement, meniscal tears, ligament injuries, osteochondral lesions, osteochondritis dissecans etc. [5].
Figure 1: X-ray of 2011 of the right wrist after proximal row carpectomy.
We want to present a case in which the SPECT/CT was very helpful (Figure 2).
Figure 2: MRI of 2011 T2 of the right wrist showing synovitis at the trapezial radial joint.
A right hand dominant 40yr old woman reported to the hospital in June 2004 with persisting pain after a right distal radius fracture. An arthroscopy shows slight synovitis of the wrist, laxity of the SL ligament and avascular necrosis of the proximal pool of the scaphoid bone. 6 Months later pain is progressing and function is decreased with 50 percent. CT-scan showed a scapholunate advanced collapse (SLAC) type III osteoarthritic wrist for which an uncomplicated proximal row carpectomy (PRC) was performed.
5 years after the operation patient returned with increasing pain of the right wrist mainly at the radial trapezium transition. MRI showed osteoarthritis at the radiocarpal transition and edema of the hamate bone and a tear in the triangular fibrocartilage complex, not responding to physiotherapy or kenacort injections. Because of persisting pain a bone scintigraphy was performed, which showed a cyst of the hamate bone, followed by arthroscopic debridement.
Because of still persisting pain a SPECT-CT was performed which showed a cyst in the hamate bone at the articulation. 3 months later thee cyst was enucleated and an arthrodesis (Figure 3) of capitate and hamate bone was performed. Control X-ray of the wrist showed a fusion of the proximal pole of the hamate and capitate interval. Radiographic control showed an increasing fusion, which is being follow-up through the outpatient clinic and improved with continuing hand therapy. With the QDash-score 43 and the PRW (H) E-DLVscore 58/150. The palmar dorsal flexion was 40-50 degrees.
Figure 3: SPECT/CT of 2011 of the right wrist showing high signal at the hamate bone, shaded with the red circles.
In this case report, SPECT/CT proved a very helpful diagnostic tool for pathology of the wrist. Several diagnostic and operative interventions during 8 years, for example; X ray, CT scanning, MR Imaging and even an arthroscopy could not identify the specific pathology and successfully treat the pain.
Disadvantages of SPECT/CT are the longer duration, to blame to the time needed to collect enough fotons. Patients have to lay very still, small movements can lead to disturbance of the images.
SPECT/CT eventually combined bone activity with localisation of the anatomical area on CT and treatment of the shown pathology was successful.
In a study by Hirschmann and co-workers, the value of SPECT/CT was demonstrated in patients with pain after surgical treatment of knee osteoarthritis [6]. They found that the SPECT/CT showed the highest value in radiological support of clinical suspected diagnoses by displaying the specific anatomical areas of the shown pathology. Furthermore diagnostic sensitivity of SPECT/CT when used to differentiate between benign and malignant bone lesions is 98.4% compared to plain SPECT with 82.5% [10,11]. A study by Stolfuss et al. showed that SPECT had a higher sensitivity for chronic osteoarthritis in foot and ankle than planar imaging (0.80 vs. 0.68, n.s.).
The advantage of SPECT was most obvious in the anatomically complex midfoot area (0.63 vs. 0.26, p<0.05) [12]. The value of SPECT/CT in specific pathology of the joints has been demonstrated in several other studies as well [3,5,6]. The current treatment by a PRC shows many patients with post-operative complaints of pain, who required daily medication and were unable to return to manual labor type jobs. Hopefully further research on the employability of SPECT/CT for chronic complaint could have some benificial effect for this population.
In this case report we could confirm the above mentioned results that SPECT/CT offers more precise localisation and thereby, the clinically suspected diagnosis was confirmed and treated successfully.
L. Musters; conception and design, provision of patient, collection/ assembly of data, data analysis/interpretation, literature search, manuscript writing.
G.A. Kraan; revising and final approval.
M. ten Broek; data analysis/interpretation
Did the author obtain written informed consent from the patient for submission of this manuscript for publication? Yes.
Ethical standards followed the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2000.
