Journal of Arthritis

ISSN - 2167-7921

Hiroshi Kawaguchi

Hiroshi Kawaguchi
Head, Spine Center
JCHO Tokyo Shinjuku Medical Center, Japan

Research Interest

Role of cytokines / growth factors in bone and cartilage, fibroblast growth factor-2 (FGF-2) on bone metabolism, tibial shaft fractures, adult articular cartilage. I am also a cutting-edge researcher in the molecular mechanism underlying anabolic action of insulin / IGF-I via the IRS1 & 2 / Akt signals during progression of osteoporosis and fracture Ialing, using patient samples and mouse genetics approaches . In addition, from the viewpoint of a molecular biologist and an orthopaedic surgeon, I have been attempting to apply several molecular signals to bone and cartilage regeneration.