Neurology and Neurorehabilitation

Yasuhiro Seta

President of SAISEIKEN Co. LTD, Tokyo, Japan


  • Case Report   
    The First in Human Case of Amyotrophic Lateral Sclerosis Treated with Stem CellDerived Conditioned Medium: A 1-Year- Follow Up
    Author(s): Minoru Ueda* and Yasuhiro Seta

    Introduction: Amyotrophic Lateral Sclerosis (ALS) is a devasting neuroinflammatory disease of the Central Nerve System (CNS) and current ALS treatments do not result in complete remission leading to death 3-5 years in most cases. Here we report the intriguing case of an ALS patient treated by transnasal and intravenous administration of stem cellconditioned medium and clinical improvement in disease severity and delay of disease progression. Case Report: In a 68-years-old male patient suffering from muscle weakness and fasciculations, progressive muscular atrophy, a variant of ALS, was diagnosed after extensive examinations ruling out other diseases in April 2019 in Yokohama city hospital and followed by Kitasato university hospital from June 2020, then finally referred to our clinic in January 2021. In our clinic, the patient received transnasal and intravenous administrati.. View More»
    DOI: .10.37532/nnr.

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