Department of Internal Medicine, University of Canterbury Christchurch, New Zealand
Review Article
Autoimmune Disease Related Molecular and Cellular Mechanisms
Author(s): Robert Wellington*
Several autoimmune illnesses are becoming more common in the
United States, according to evidence. As a result, the
expense of clinical management of autoimmune disorders to the
public health is increasing. Both genetic and environmental
variables play a role in the onset and course of autoimmune
disorders. Autoantibodies can be caused by deficiencies in key
proteins that are normally involved in maintaining the internal
environment's checks and balances. Autoimmunity has been
linked to structural anomalies or a decrease in normal levels
of the pentraxins (serum amylase P protein, acute phase proteins,
complement, and C-reactive proteins). The quality and amount of
subsequent immune responses are determined by the type of
ligand/receptor interactions that promote physical recruitment of
various signals within the cell. CD95, also known.. View More»
