Journal of Biology and Today's World

ISSN - 2322-3308

Philis Yann

Hormonology Laboratory, Amiens University Hospital, Amiens, France


  • Research Article   
    Comparison between Calculated Bioavailable Testosterone Level with Radio-Immunoassay Result
    Author(s): Philis Yann* and Soyez Marion

    Bioavailable Testosterone (BT) is henceforth well-known to be much more useful than Total Testosterone (TT) for interpretation. BT is mostly explored in case of suspicion of hypogonadism in men or hyperandrogenism in women. The reference technique to assay BT is ultracentrifugation, but Radio-Immuno Assay (RIA), which is much less expensive and easier to accomplish is the most widely used technique in practice. Several calculations are available but the one that give the better results seem to be the optimized calculation of the Vermeulen equation by Giton. Very few comparisons between BT assayed and BT calculated have been made in routine, hence our study. This is a prospective study which has included 269 patients (whose 189 men) to compare both results in the frame of matched data. Different subgroups, depending on gender, age, TT values, SHBG values and albumin values have been st.. View More»
    DOI: 10.35248/2322-3308.21.10.011

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