Department of Tissue Engineering and Applied Cell Sciences, School of Physics, College of Science, University of Tehran, North-Kargar Street, Tehran, Iran
Research Article
Design and Fabrication of Sculptured Thin Films for Application in Control of Cancer and Other Cells
Author(s): Fahimeh Farid Shayegan, Hadi Savaloni*, Hakimeh Zali and Zahra Niknam
Given the importance of cell colonization for use in tissue engineering and for studying the inhibition of cancer cells, the use of bio material sculptured nano-structures mimicking the structure of the extracellular matrix offers a unique perspective. In this study, Mn and ZnS sculptured nano-structured fabricated using Oblique (OAD) and Glancing (GLAD) angle vapor deposition methods for investigation of cell behavior. Different characteristics of the produced sculptured thin films of Mn and ZnS materials in form of helical square and 3 and 5-fold helical star shapes were obtained from XRD, FESEM, and AFM analyses. Measurement of contact angle classified the produced samples in two groups of hydrophilic and hydrophobic samples, which provided the opportunity to investigate their function when cultured with normal and cancerous cells. Results showed that the hydrophilic surfaces incre.. View More»
DOI:
10.35248/2322-3308.25.14(1).003
