Journal of Neurology & Neurophysiology

ISSN - 2155-9562

Abhishek Chaturbedi

Associate Professor and Head, Department of Neurosurgery, Manmohan Memorial Medical College and Teaching Hospital, Swoyambhu, Kathmandu, Nepal


  • Case Series   
    Dabigatran, A Direct Thrombin Inhibitor (DTI) as the First Line Treatment for Cerebral Venous Thrombosis. An Updated Case Series
    Author(s): Abhishek Chaturbedi* and Jitendra Thakur

    Background: Cerebral venous sinus thrombosis (CVST) is a rare form of stroke which still carries significant morbidity and mortality. Previous treatment regimen pertained to primarily medical therapies, with use of anticoagulants like Coumadin and Heparin. However the advent of Direct Thrombin Inhibitors (DTI) which do not need regular monitoring of blood coagulation panel and has better safety profile than Coumadin, has been suggested as a treatment modality for CVST in recent literature. Case Description: It is a case series of 7 adult patients presenting with intracerebral hemorrhage secondary to CVST from occlusion of dural venous sinuses. Dabigatran, a DTI was used as the primary treatment modality for a period of 6 months for 5 patients who had identifiable underlying cause and lifelong for 2 patient who had.. View More»

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