Wang Yuan
China
Research Article
Research of Xinfeng Capsule on Pulmonary Function in Adjuvant Arthritis Rats Based on the Effects of B, T Cell Immunity
Author(s): Wan Lei, Liu Jian, Huang Chuanbing and Wang YuanWan Lei, Liu Jian, Huang Chuanbing and Wang Yuan
Objective: to observe the effects of Xinfeng Capsule on adjuvant arthritis rat model of pulmonary function, B, T cell immunity. Methods 40 rats were randomly divided into normal, model, Tripterygium Glycosides tablet and XFC group. Except the normal group, the other rat’s right rear paw intradermal injection of Freund’s complete adjuvant induced arthritis in 0.1 mL. Inflammation induced 19 d after administration, the normal group, the model groups were given physiological saline, rats in the treatment group were given of Xinfeng Capsule (2.4 g/kg), Tripterygium Glycosides tablet (10 mg/kg), once a day, continuous administration of 30D. Joint inflammation in rats was observed performance, flow cytometry detection of peripheral blood B, T lymphocyte attenuator (BTLA), regulatory T cells (Treg) and surface markers of forkhead transcription factor (FoxP3) expr.. View More»
