Emerging digital technologies are continuing to advance, presenting unprecedented prospects for improving healthcare service delivery in health systems throughout the world. Substantial progress has been made in the field of healthcare. However, the absence of emotional recognition, along with a scarcity of tailored and ubiquitous health apps and emotive smart devices, necessitates the use of developing technologies to integrate intelligent sensors into health systems. Although great progress has been made in smart and connected health care, more research innovation, dissemination, and technology are required to unbundle new prospects and advance towards healthcare 5.0. Healthcare is on the verge of a paradigm shift that will usher in a new era of smart illness diagnosis and control, virtual care, smart health management, smart monitoring, and smart decision-making. As a result, this research investigates the roles and capabilities of sensors as well as other new technologies, including nanotechnology, 5G, drone technology, blockchain, robots, big data, the internet of things, artificial intelligence, and cloud computing. Patient remote monitoring, tracking, and virtual clinics; emotional telemedicine; ambient supported living; smart self-management; wellness monitoring and control; smart treatment reminders; compliance and adherence; and tailored and linked health care are all available through Healthcare 5.0. Building a resilient and robust healthcare 5.0, on the other hand, is not without its difficulties. Individual attitudes, mismatch with hospitals' goals, lack of money, and religious and cultural hurdles have all been mentioned as potential barriers to the successful adoption of healthcare 5.0. As a result, robust, technology-driven healthcare systems are required. Expanding technological infrastructure, providing budgetary support based on sustainable business models, developing appropriate legal and e-health policies, standardising and synchronising protocols, improving stakeholders' engagement and involvement, and establishing private and public partnerships and investments are all needed to achieve this.
