Sapna Ratan Shah
Clopidogrel is a cholesterol-lowering drug it can help to prevent more plaque from forming. In this present model the effects of Clopidogrel on viscosity of blood has been obtained. This problem of non-Newtonian and non-linear blood flow through a stenosed artery is solved numerically where the non-Newtonian rheology of the flowing blood is characterized by the generalized Power-law and Bingham plastic fluid models. The proposed model are solved and closed form expressions for the blood flow characteristics namely, velocity profile, volumetric flow rate, pressure gradient, resistance to flow, wall shear stress and apparent viscosity are derived. The effects of various parameters entering into problem are discussed with the help of graphs. It has been found that the wall shear stress and resistance to flow and viscosity increases with the non-Newtonian behavior index of the blood as well as tube radius for constant value of the stenosis height for both fluid models but these increases are comparatively small in Power-law fluid model. It has been concluded that the patients entangled to cardiovascular diseases due to blood clots can prevent by giving the regular doses of Clopidogrel in order to dilute the blood. This lowers the blood viscosity. Clopidogrel would be more helpful in the functioning of diseased arterial circulation. This work may be help in diagnosis and treatment of cardiovascular disorders as well as people working in biomedical field.
