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Using real time PCR for the etiological diagnosis of viral enceph | 48299

Journal of Neurology & Neurophysiology

ISSN - 2155-9562

Using real time PCR for the etiological diagnosis of viral encephalitis

3rd International Conference and Exhibition on Neurology & Therapeutics

September 08-10, 2014 Hilton Philadelphia Airport, USA

Carlos Jorge Rubinstein

Accepted Abstracts: J Neurol Neurophysiol

Abstract :

Viral infections of the central nervous system (CNS) represent a challenge for early diagnosis and proper treatment of the disease. Different studies should be performed on the patient in order to arrive at an accurate diagnosis. The electroencephalogram, magnetic resonance imaging, viral culture, serological and cytochemical analysis are important tools to diagnose this disease. However, the polymerase chain reaction (PCR) or conventional PCR has become the gold standard for the diagnosis of viral encephalitis. Indeed, Real Time PCR (RT-PCR) equipments are replacing the conventional PCR ones. Faster results may be an explanation of this fact. Information obtained from dissociation curve analysis of the RT-PCR technique represents a highly sensitive and specific tool for the Herpes simplex (HSV), Varicela (VZV), Cytomegalovirus (CMV) and Enterovirus (EV) detection.

Biography :

Carlos Jorge Rubinstein is a medical specialist in Psychiatry, Geriatrics and Internal Medicine. He is a professor at the School of Medicine, University of Buenos Aires and Head of Research and Teaching in the School Hospital Dr. Federico Abete Malvinas Argentinas.

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