Spinal Cord Fusion in Acute Spinal Cord Injury of Dog | 49506

Journal of Neurology & Neurophysiology

ISSN - 2155-9562

Spinal Cord Fusion in Acute Spinal Cord Injury of Dog

13th International Conference on Neurology and Neurosurgery

June 19-21, 2017 Paris, France

Xiaoping Ren

Hand and Microsurgery Center, The second Affiliated Hospital of Harbin Medical University, China
State-Province Key Laboratories of Biomedicine-Pharmaceutics, Harbin Medical University, China
Heilongjiang Medical Science Institute, Harbin Medical University, China
Loyola University Chicago, USA

Keynote: J Neurol Neurophysiol

Abstract :

Employing an acute dog model of spinal cord injury (SCI) using a diamond knife to generate a clean cut with little crush injury, we show that application of PEG preparations on the severed ends effects considerable neuroprotection and repair. Our results show that electrical continuity starts to be detected one hour after injury, and that BBB scores reach approximately 50% of the sham levels after three to four weeks. This level of restoration of function continues out to 6 month, which is the longest we assessed the dog. Neurophysiological and DTI MR data confirm electrophysiological and anatomical continuity. This study suggests that a form of spinal cord injury can effectively be treated and points out a way to treat spinal cord injury patients by removing the injured segment and, along with vertebral shortening, reapproximating and fusing the two stumps.

Biography :

Xiaoping Ren received his M.D in Harbin Medical University in 1984. He performed his Clinical and Research Hand Fellowship training in University of Louisville in Kentucky (1996-2000). Currently, he has professor position in Harbin Medical University in China and adjunct faculty in Loyola University Chicago in US. Dr. Ren has had over 60 publications in peer-reviewed journals and he is holding active Memberships of the American Association for Hand Surgery, Orthopedics and Neurological of American Academy and the American Heart Association. He also service as peer-reviewer of several journals. As well as practice as a Hand and Microsurgeon in clinic, his research interest is on protective strategies against ischemia/reperfusion of CNS and SCI functional recovery.