Naksidil Torun Yazihan, Sinan Yetkin and Emrah Kizilay
Gulhane Military Medical Academy, Turkey
Posters & Accepted Abstracts: J Neurol Neurophysiol
Aim of this study: To investigate the sleep parameters, spindle characteristics and cognitive functions of first epizod drug naive psychotic patients (Brief psychotic disorder, shizophreni form disorder and shizophrenia). In the context of this study we are expecting to understand different dimensions of the clinical characteristics of the disorder by investigating the sleep structure and its relationship with the cognitive functions. Methods: The study sample consisted of 19 drug naive male inpatients between the age of 20 and 25; who has non-effective first epizod psychotic disorder diagnose and whose year of education is at least 8. The healthy controls were similar according to age, sex and duration of education. Sleep parameters were included some macro (sleep structure and sleep contunuity) and micro (sleep spindle) variables. We conducted two days polisomnographic recording consequently. We evaluated some congnitive functions such as memory, attention, learning, verbal fluency, working memory by neuropsychological tests. We are continuing our statistical analyses on our sample. Our dependent variables are sleep latence, REM latence, duration of REM and stage 2, sleep period time, sleep efficiency index; sleep spindle dencity, frequency and amplitude; some neuropsychological test scores,as well. Results: The variables were peak frequency (controls =12.71, Sd= 0.54; patients =12.78; Sd= 0.52) mean frequency (controls =12.58, Sd= 0.77; patients =11.18; Sd= 0.52), duration, (controls =0.97, Sd= 0.96; patients =1.04, Sd= 0.96) amplitude (controls =38.68, Sd= 6.26; patients =37.51; Sd= 2.21), spindle density (controls =0.64, Sd= 0.33; patients =0.56; Sd= 0.17) and spindle activity (controls =38.34, Sd= 7.86; patients =39.03; Sd= 5.00) .
Email: drcib50@gmail.com
