Prenatal stress potentiates febrile seizure in human offspring | 48892

Journal of Neurology & Neurophysiology

ISSN - 2155-9562

Prenatal stress potentiates febrile seizure in human offspring

8th European Neurology Congress

September 21-23,2016 Amsterdam,Netherlands

Sedra Mohammadi, EhsanSaboory, Peyman Gholipoor, Ahad Ghazavi, Arezoo Kiyani and Shiva Roshan-milani

Urmia University of Medical Science, Iran
Tabriz University of Medical Sciences, Iran

Scientific Tracks Abstracts: J Neurol Neurophysiol

Abstract :

Introduction & Aim: A febrile seizure is a neurological disorder that occurs following an infection that results in a rapid rise in body temperature. It commonly affects 3ΓΆΒ?Β?5% of children between the ages of 3 months and 5 years. There is evidence suggesting that neurological disorders can be exacerbated in an offspring that was exposed to stress prenatally. This study aimed to investigate severity of febrile seizures in prenatally stressed offspring. Method: In the current study, 158 children under 2 years old with febrile seizure were selected. Information about convulsion including seizure lasting, recurrence of seizure, age of first seizure and type of febrile seizure (simple or complex) were obtained. Questionnaire to evaluate the perceived stress and exposure to major stress during pregnancy was completed. Results: This finding showed that both high score of perceived stress and exposure to major stress during pregnancy significantly increased seizure lasting and seizure intensity. Exposure to prenatal stress did not have any significant effects on recurrences of febrile seizure and on age of onset of first febrile seizure. Also, appearance of complex febrile seizure was significantly higher in children born from mothers with major-stress exposure compared to unexposed one. Conclusion: This study indicated that there is a significant positive relationship between both higher perceived stress score and exposure to major stresses during pregnancy with seizure parameters in offspring.

Biography :

Sedra Mohammadi is pursuing her Medicine from the Urmia University of Medical Science. She is a Member of Student Research Committee of Urmia University of Medical Science since 2014. She has published 2 papers in journals and has been serving as a Redactor of Scientific Journal of Student Research Committee.