Contiguous involvement of brain and spinal cord by plasma cell granuloma: A rare presentation

Journal of Neurology & Neurophysiology

ISSN - 2155-9562

Contiguous involvement of brain and spinal cord by plasma cell granuloma: A rare presentation

Joint Event on 25th International Conference on Neurology: Neurochemistry Neuropharmacology and Neurosciences & International Conference on Neurooncology and Neurosurgery

September 17-18, 2018 Dubai, UAE

Ritesh Nawkhare and Pandey P

Bangur Institute of Neurosciences, India

Scientific Tracks Abstracts: J Neurol Neurophysiol

Abstract :

Plasma cell granuloma of the Central Nervous System (CNS) is a rare entity. Primary intracranial lymphoma was first reported by West et al. in 1980 with around 60 cases reported till date. Previously reported locations include meninges, cerebral hemispheres, ventricles, hypothalamus, sellar region and cerebellum. Intracranial plasma cell granuloma is characterized radiologically by its extra axial, dural based location and homogeneous enhancement with contrast. Owing to it, meningioma, tuberculoma, sarcoidosis and wegners granulomatosis comprise important differential diagnosis. Plasma cell granuloma is generally a benign, non-recurring lesion. Treatment options for plasma cell granuloma include total/subtotal excision, steroids and radiotherapy. Technically inaccessible sites have been treated with biopsy followed by steroid therapy. In majority of cases a single plasma cell granuloma has been reported in the brain or spinal cord. Only two cases of plasma cell granuloma simultaneously involving the brain and spinal cord have been reported. We believe this is the first case showing a single lesion contiguously involving the brain and spinal cord in its extent and was managed surgically and discuss its clinical, radiological and pathological findings along with review of literature.

Biography :

Ritesh Nawkhare is a Neurosurgeon, recently completed his Post-doctorate training in Neurosurgery. His areas of core interest lies in cranial oncology and craniovertebral junction. Currently he works as a Senior Resident at one of the biggest neurosciences institute of eastern India, Institute of Post-Graduate Medical Education and Research (IPGMER) and Seth Sukhlal Karnani Memorial Hospital (SSKM) Hospital.

E-mail: [email protected]