Application of Quantitative Dynamic Whole-Body 18FDG-PET/CT in th | 48721

Journal of Neurology & Neurophysiology

ISSN - 2155-9562

Application of Quantitative Dynamic Whole-Body 18FDG-PET/CT in the differential Diagnosis of Pulmonary Nodules

7th Global Neurologists Annual Meeting on Neuro Surgery and Interventional Radiology

August 22-24, 2016 Vienna, Austria

Jianhua Zhang

Peking University First Hospital, China

Scientific Tracks Abstracts: J Neurol Neurophysiol

Abstract :

18F-FDG PET/CT imaging has become a crucial component of oncological management for a wide variety of malignancies and is routinely used in staging, restaging and treatment response assessment tasks. Compared to qualitative method and semi-quantitative method, quantitative method is more accurate and can overcome the limitations of the routine methods, but it is more complicated on the management of many cancer patients. As for the quantitative method, plasma input function and FDG influx rate constant (Ki) are indispensable. An emphasis in the present work is to develop non-invasive plasma input function estimation techniques in order to facilitate clinical acceptance. Image derived input function method will be studied and validated in the novel context of whole body dynamically-acquired images to facilitate parametric imaging. The present work is expected to significantly enhance the capability of dynamic whole body FDG PET/CT imaging to quantify the kinetics of FDG, and in turn, has the long-term potential to significantly enhance diagnostic, prognostic and treatment response monitoring capabilities of the FDG PET imaging modality and to fundamentally alter routine clinical practice.

Biography :

Jianhua Zhang has completed his M.S. in 2004 and M.D. studies in 2012 from Peking University, majoring in Radiology and Nuclear Medicine. He joined the faculty of nuclear medicine at Peking University First 2004 and now is the associate professor. He has published more than 20 papers in journals and 20 chapters in proceedings and medical textbooks. The research interests of Dr. Zhang include application of positron emission tomography (PET) in studies of tumors, especially the lymphoma, and quantitve analysis. He has mentored 1 doctoral student and has been involved in teaching of more than 30 residents.