Computational science is a discipline concerned with the design, implementation and use of mathematical models to analyse and solve scientific problems. Typically, the term refers to the use of computers to perform simulations or numerical analysis of a scientific system or processComputational science, also known as scientific computing or scientific computation (SC), is a rapidly growing branch of applied
computer science and mathematics that uses advanced computing capabilities to understand and solve complex problems. It is an area of science which spans many disciplines, but at its core, it involves the development of models and simulations to understand natural systems. Algorithms (numerical and nonnumerical): mathematical models, computational models, and computer simulations developed to solve science (e.g., biological, physical, and social), engineering, and
humanities problems.Computer hardware that develops and optimizes the advanced system hardware, firmware, networking, and data
management components needed to solve computationally demanding problems.The computing infrastructure that supports both the science and engineering problem solving and the developmental computer and information science
In practical use, it is typically the application of computer
simulation and other forms of computation from numerical analysis and theoretical
computer science to solve problems in various scientific disciplines. The field is different from theory and laboratory experiment which are the traditional forms of science and engineering. The scientific computing approach is to gain understanding, mainly through the analysis of mathematical models implemented on computers. Scientists and engineers develop computer programs, application software, that
model systems being studied and run these programs with various sets of input parameters. The essence of computational science is the application of numerical algorithms and/or computational mathematics. In some cases, these models require massive amounts of calculations (usually floatingpoint) and are often executed on supercomputers or distributed computing platforms. Actually the science which deals with the Computer Modeling and
Simulation of any physical objects and phenomena by high programming language and software and hardware is known as Computer Simulation.The term computational scientist is used to describe someone skilled in scientific computing. This person is usually a scientist, an engineer or an applied mathematician who applies highperformance computing in different ways to advance the stateoftheart in their respective applied disciplines in physics, chemistry or engineering.Computational science is now commonly considered a third mode of science, complementing and adding to experimentation/observation and theory (see image on the right).Here, we define a system as a potential source of data, an experiment as a process of extracting data from a system by exerting it through its inputs and a
model (M) for a system (S) and an experiment (E) as anything to which E can be applied in order to answer questions about S. A computational scientist should be capable ofrepeat cycle until a suitable level of validation is obtained: the computational scientists trusts that the
simulation generates adequately realistic results for the system, under the studied conditions In fact, substantial effort in computational sciences has been devoted to the development of algorithms, the efficient implementation in programming languages, and validation of computational results. A collection of problems and solutions in computational science can be found in Steeb, Hardy, Hardy and Stoop .Philosophers of science addressed the question to what degree computational science qualifies as science, among them Humphreys and Gelfert. They address the general question of epistemology: how do we gain insight from such computational science approaches. Tolk[9] uses these insights to show the epistemological constraints of computerbased
simulation research. As
computational science uses mathematical models representing the underlying theory in executable form, in essence, they apply modeling (theory building) and
simulation (implementation and execution). While
simulation and computational science are our most sophisticated way to express our knowledge and understanding, they also come with all constraints and limits already known for computational solutions
High Impact List of Articles
Conference Proceedings

Chemokines and autism spectrum disorder: A literature review
Gislei F. Aragao, Nathalia de O. Pires, Ana Paula G. dos Santos Castro, Isabelle Magalhaes Albuquerque, Carla Larissa de C. Vieira, Daniel G.Britto, Nayrene Amorin C. de Oliveira, Kelly Rose T. Neves, Leila Veronica da C. Albuquerque and Tatiana Paschoalette R. Bachur Posters & Accepted Abstracts: Journal of Neurology & Neurophysiology

Studying the effectiveness of venlafaxine in mice model of post traumatic stress disorder
Natalia Malikowska and Kinga SaÃ?Â?at Scientific Tracks Abstracts: Journal of Neuroscience and Neuropharmacology

Measure the knowledge, attitude and practice of people in head injury
Akram A Alandijani, Abdulqader I Susi, Hammam N Albeshr, Hassan M Barnawi and Ahmad Alharbi Posters & Accepted Abstracts: Journal of Neurology & Neurophysiology

Canavan?s disease as a model for development of efficacious, sustainable and safe rAAV gene therapeutics for CNS disorders
Guangping Gao Scientific Tracks Abstracts: Journal of Neurology & Neurophysiology

Cabernet sauvignons from france do trigger migraine more often than those from south america: An open prospective study
Abouch Valenty Krymchantowski Accepted Abstracts: Journal of Neurology & Neurophysiology
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