Disease-modifying anti rheumatic
drugs (DMARDs) is a category of otherwise unrelated
drugs defined by their use in rheumatoid
arthritis to slow down disease progression. The term is often used in contrast to no steroidal anti-inflammatory drug and
steroids The term "ant rheumatic" can be used in similar contexts, but without making a claim about an effect on the course. Other terms that have historically been used to refer to the same group of
drugs are "remission-inducing drugs" and "slow-acting anti-rheumatic drugs”. Although the use of the term DMARDs was first propagated in rheumatoid
arthritis (hence their name) the term has come to pertain to many other diseases, such as Crohn's disease, lupus
erythematosus (SLE), Sjögren syndrome, immune thrombocytopenic purpura (ITP), myasthenia gravis, sarcoidosis and various others.The term was originally introduced to indicate a drug that reduce evidence of processes thought to underlie the disease, such as a raised erythrocyte sedimentation rate, reduced haemoglobin level, raised rheumatoid
factor level and more recently, a raised C-reactive protein level.[citation needed] More recently, the term has been used to indicate a drug that reduces the rate of damage to bone and cartilage. DMARDs can be further subdivided into traditional small molecular mass
drugs synthesised chemically and newer "biological" agents produced through
genetic engineering Some DMARDs are mild chemotherapeutics but use a side-effect of chemotherapy—immunosuppression—as its main therapeutically benefit. Anti-rheumatic
drugs journals has been successfully publishing quality Research
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