Journal of Pharmaceutical Sciences and Drug Development

Quanyi 'Charlie' Li

Quanyi 'Charlie' Li
Senior Scientistm, Development Services, MilliporeSigma


Quanyi Li, Ph.D. received his Ph.D. in Molecular Biology in 1990 in China where he studied bacteria plasmid genetics and its applications in plant sciences. Then, he received his postdoctoral trainings in UK from 1991 to 1997. His first postdoc was in molecular virology in Department of Microbiology, The University of Reading. His study was in understanding poliovirus replication and the genetic minimal requirements for a poliovirus replicon. His second postdoc was in Department of Genetics, The University of Nottingham where he studied human molecular genetics and genomics. His study had led to the discovery of TBX5 gene for Holt-Oram syndrome, a rare heart and hand defects in newborn children. In 1999, he moved to America and continued his biomedical research in University of Pennsylvania, and Columbia University for understanding human diseases using his knowledge and skills in genetics and genomics. The past ten years, his interests in nucleic acids ?based molecular assays development has driven him working in mycoplasma detection, environmental microbiology for testing viruses in drinking water, fungi and bacteria in environments. He was one of metagenomics researchers using next-generation sequencing technologies for studying the microbial communities in environmental samples for monitoring and understanding the micro-eco environments. Currently, he works on the development of molecular assays and GMP tests for adventitious viruses, mycoplasma, bacteria and fungi in biopharmaceutical manufacturing and products.

Research Interest

Dr. Li?s research interests are in genetic based nucleic acids assay development for microorganisms including viruses, mycoplasma, bacteria and fungi. He also works on assay validation and GMP testing development for biopharmaceutical industries.