Journal of Pharmaceutical Sciences and Drug Development

Jozef Prandota

Jozef Prandota
Emeritus Professor of Pediatrics & Clinical Pharmacology Former Senior Fulbright-Hays, Program and The Kosciuszko Foundation
Wroclaw Medical University, Wroclaw, Poland


Dr Joseph Prandota received his Doctor of Medical Sciences degree (1970) and PhD degree (1980) from Wroclaw Medical University, Poland. He worked as Assistant/Adjunct in Dpt of Pharmacology (1966-1975), Dpt of Pediatric Nephrology (1975-1977), the Associate Professor, Full Professor and Chief in Dpt of Pediatrics, J. Korczak Memorial Children?s Hospital in Wroclaw (1978-2002), and then in the Faculty of Dentistry, and as the Chair and Head of Dpt of Social Pediatrics, Faculty of Health Sciences, Wroclaw Medical University (2002-2011). He received the Senior Fulbright-Hays Program award and worked in Dpt of Pediatrics, Emory University School of Medicine, Atlanta, GA (1973-175; director dr Albert W. Pruitt); obtained fellowship in Dpt of Pharmacology, Creteil, Paris XII, France (1977/1978; chairman dr Jean-Paul Tillement); was awarded The Kosciuszko Foundation Fellowship (twice) working in Dpt of Pediatrics, LSU in Shreveport, LA (1986); director dr John T. Wilson; and was a Visiting Professor in Dpt of Pediatrics and Pediatric Nephrology, School of Medicine, Hannover, Germany (September, 1993; chairman dr Johannes Brodehl). He published 65 peer-reviewed papers as the only or first author, and solved several important scientific/clinical puzzles, such as for example: the peculiar disposition of drugs in cystic fibrosis patients, the dangerous diuretic tienilic acid-coumarin derivatives interaction, the aquarium fish food proteins as the triggering agents in development of autoimmune hepatitis, the possible accumulation of cimetidine after multiple oral doses, the need for calculation of plasma elimination half-life of drugs only after reaching steady-state concentration, and an important role of viral infections in inhibition of xenobiotic metabolizing enzymes leading to development of autoimmune hepatitis. Dr Prandota demonstrated that T. gondii may cause different types of recurrent headaches (Am J Ther, 2007,14,63). He is an Editor of more than 35 scientific journals including World J Clin Pediatrics (China), Int J Neurology Res (Hong Kong), Archives of Clinical Hypertension (India), Global Journal of Gastroenterology & Hepatology (UK), and The Open Neurology Journal (USA). Recently, Dr Prandota et al found the increased seroprevalence of chronic toxoplasmosis in autistic children [Int J Neurol Res, 2015,1(3),102], and suggested that T. gondii may be responsible for development of atherosclerosis (J Cardiol Ther, 2017,4(2).611), and play a crucial role in triggering autoimmune diseases (IJNR, 2018,4(1),379).

Research Interest

Latent chronic T. gondii infection and its participation in development of molecular pathomechanisms of headaches, several neurodegenerative, and autoimmune diseases, including autism, inflammatory bowel disease, Lesniowski-Crohn disease, cryptogenic liver disease, steatohepatitis, diabetes mellitus, atherosclerosis, idiopathic intracranial hypertension, and proteinuria.