Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria, Nigeria
Research Article
Antibacterial Activity of ? and ? Amyrin Isolated from Morinda lucida against Some Multidrug Resistant Enterobacteriaceae
Author(s): Mshelia M.B*, G.O. Adeshina, J.A. Onaolapo, A.M. Musa, E.H. Mshelia, M.S. Salihu, D.L. Muammar, A.A. Sadam, G. Dauda and Rabiu H
Introduction: Enterobacteriaceae is a family of gram negative bacteria often associated with the gut. They were found to be responsible for a large proportion of serious and life-threatening infections due to the increasing resistance to available antibiotics. In many developing countries different parts of Morinda lucida has been used as herbal medicine. The aim of this study was to isolate compound(s) from the most active fraction of M. lucida leaves and to test the activity against some multidrug resistant Enterobacteriaceae.
Methods: M. lucida leaves were freshly obtained, shade-dried, grinded and extracted with methanol. This was further fractionated using column chromatography. The different fractions obtained were tested for antibacterial activity against some multidrug resistant members of Enterobacteriacea.. View More»
DOI:
10.35248/2322-3308-14.1.011
