Department of Medical Microbiology, College of Medicine, University of Al-Qadisiyah, Diwaniyah, Iraq
Research Article
Evaluation of serum interleukin-17 and tumour necrosis factor-? levels in patients with vitiligo
Author(s): Israa A Dheeb and Husam Awad*
Background: According to definitions, vitiligo is an acquired cutaneous complicated condition caused by functional melanocyte loss in the epidermis. It is characterised by milky white macules of diverse sizes and shapes that have a tendency to grow peripherally over time. Cytokines play a critical role in the depigmentation process of vitiligo and control the immune response and inflammation. Objective: The present study aimed to estimate the serum levels of proinflammatory cytokines, interleukin 17, and tumour necrosis factor alpha in vitiligo patients and healthy subjects. Materials and Methods: In order to conduct the study, samples from 60 patients were collected and samples from 60 healthy participants (the control group) were pooled and measured using sandwich ELISA. Data on the patient's age, sex, family history, disease state, stress exposure, and males smoking are collect.. View More»