Radiation Oncology Department, UPMC, Whitfield Clinic, Waterford, Ireland
Brain metastasis: How to predict and when not to treat?
Author(s): Esam Abdelaal*, Delahunty K, Kehoe M, Hacking D, Deek B, O’Sullivan K, Totten P, O’Leary A, Barry A and Fagan K
Background: Brain Metastasis (BM) is the commonest intracranial neoplasm in adults. There are different treatment approaches for BM including Whole Brain Radiotherapy (WBRT) which is used mainly for patients with multiple lesions and those unfit for Stereotactic Radiotherapy (SRS) or surgery (S). Multiple prognostic indices have been developed for better patient selection for treatment and to identify patients with very short survival. We analyzed the survival for patients with brain metastasis and investigated some predictive factors for survival and we studied a small subset of patients with lung cancer without BM to look into some predictive factors for development of BM. Material and Methods: We retrospectively analyzed data of patients with radiologic diagnosis of brain metastasis who underwent whole brain radiotherapy either alone or with other local treatment modaliti.. View More»
DOI: 10.35248/ clinical-oncology.4(1).2-11