MAP Centre for Urban Health Solutions, St. Michael’s Hospital, Toronto, Canada
Research Article
Barbiturates versus Benzodiazepine for the Treatment of Severe Alcohol Withdrawal Syndrome: A Systematic Review and Meta-Analysis of Clinical Trials
Author(s): Blerina Asllanaj*, Eric Chang, Maha Awaiz Hassan and Yi McWhorter
Context: The utility of phenobarbital in the treatment of severe alcohol withdrawal
is contentious.
Objective: The aim was to conduct a meta-analysis of existing observational and
randomized controlled trials investigating the efficacy and safety of phenobarbital versus commonly used benzodiazepine in the setting of severe alcohol withdrawal.
Data sources: A search of PubMed, Medline, Embase, and the Cochrane Central
Register of Controlled Trials published between 1976 and September 2021 was
performed using medical subject headings: “severe alcohol withdrawal”, “Delirium
Tremens” (DT), “Phenobarbital” (PB), “barbiturate”, “critical care”, “ICU”, “Trial”,
“human” and “English”. We select.. View More»
DOI:
10.35248/2322-3308-11.4.005
