Journal of Multiple Sclerosis

ISSN - 2376-0389
NLM - 101654564

Eliot Joy

Department of Opthamology, University of East London, United Kingdom


  • Commentry   
    Multiple sclerosis and Neuromyelitis Optica Spectrum Disorders and the Role of Spinal Cord
    Author(s): Eliot Joy*

    Spinal cord involvement is a crucial explanation for disability in patients with MS or neuromyelitis optica spectrum disorders (NMOSDs). Multiple sclerosis and NMOSDs are often distinguished from other disorders that cause myelopathy by results from laboratory and radiological investigations. However, limitations within the sensitivity and specificity of medulla spinalis imaging and poor correlation with disability megasures have impeded the understanding of the connection between medulla spinalis involvement and clinical manifestations. Nevertheless, studies of the pathological features of MS and NMOSDs have shown that quantitatively different mechanisms cause differences in clinical course and pattern of accrual of permanent disability in the two disorders. Better understanding of those mechanisms is important to develop more informative clinical measures, electrophysiological metho.. View More»

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