Department of Internal Medicine, World Citi Medical Center, Quezon City, Philippines
Case Report
Posterior Reversible Encephalopathy In Systemic Lupus Erythematosus: A rare Case Report
Author(s): Daphne Angelie Sevilleja*
Systemic lupus erythematosus (SLE) is known to be a multisystem autoimmune disorder. Neuropsychiatric manifestations of systemic lupus erythematosus (SLE) are heterogenous and complex. Posterior reversible encephalopathy syndrome (PRES) and its association with SLE has increasingly, been recognized. PRES as an initial manifestation of SLE is not widely reported in the literature. A case control study reported prevalence of PRES in SLE as much as 0.43%. Common presentations include headache, vomiting, altered mental function, visual symptoms, and seizures. Diagnosis is supported by classical symptoms and typical radiological feature of bilateral posterior subcortical brain edema on magnetic resonance imaging (MRI). PRES is linked with accelerated hypertension, renal impairment, eclampsia, pre-eclampsia, sepsis, cytotoxic therapy, underlying autoimmune diease, and immunosuppressive ther.. View More»
