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Journal of Neurology & Neurophysiology

ISSN - 2155-9562

Daniel Trivedi

Department of Neurosciences, London, United Kingdom

Publications
  • Opinion Article   
    Pathophysiology and Prognosis of Parkinson's Disorder
    Author(s): Daniel Trivedi

    The vitally neurotic attributes of PD are cell demise in the mind's basal ganglia (influencing up to 70% of the dopamine-emitting neurons in the substantia nigra standards compacta before the finish of life). In Parkinson's infection, alpha-synuclein becomes misfolded and cluster along with other alpha-synuclein. Cells can't eliminate these clusters, and the alpha synuclein becomes cytotoxic, harming the cells. These clusters can be found in neurons under a magnifying instrument and are called Lewy bodies. Loss of neurons is joined by the passing of astrocytes (star-molded glial cells) and a huge expansion in the quantity of microglia (one more kind of glial cell) in the substantia nigra. Braak organizing is a method for clarifying the movement of the pieces of the mind impacted by PD... Read More»

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