Journal of Multiple Sclerosis

Editorial Office, Journal of Multiple Sclerosis, Belgium

Publications

• Mini Review   
  Review of the Autonomic Nervous System's Function in Controlling Cerebral Blood Flow in Dementia
  Author(s): Andrew Spencer*
  
  In this review, we'll look at how the autonomic nervous system affects dementia patients' Cerebral Blood Flow (CBF). As the world's population ages, the 55 million people who already have dementia will grow in number. Understanding the alterations in vascular physiology associated with dementia may open the door to cutting-edge therapeutic strategies. Numerous dementia subtypes have been shown to have decreased CBF as well as increased cerebrovascular resistance and decreased vasoreactivity. Despite declines in global and regional CBF, Cerebral Autoregulation (CA), a crucial mechanism for maintaining cerebral perfusion, is mostly unaffected by cognitive impairments. Dementia results in a loss of Neurovascular Coupling (NVC), which may be a major cause of cognitive dysfunction. Despite a large number of research examining CBF regulation issues in dementia, less is known abo.. View More»
  DOI: 10.35248/2376-0389.22.9.6.448

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