Woo-Kyoung Yoo
Department of Physical Medicine and Rehabilitation, Hallym University College of Medicine,
Republic of Korea
Research Article
DTI Findings Correlated with Neurocognitive Impairments in Basal Ganglia
Stroke: A Preliminary Study
Author(s): Kwang-Ik Jung, Ah-Young Jun, Yun-Hee Kim, Shahid Bashir, Suk Hoon Ohn, SeungHo Ahn, Chang-hyun Park and Woo-Kyoung YooKwang-Ik Jung, Ah-Young Jun, Yun-Hee Kim, Shahid Bashir, Suk Hoon Ohn, SeungHo Ahn, Chang-hyun Park and Woo-Kyoung Yoo
Objective: Subcortical lesion involving basal ganglia can cause a wide range of behavioral and cognitive
alterations largely attributed to disconnection of subcortical fibers; however, the underlying neural correlates of
cognitive dysfunction based on the integrity of the white matter fiber has not yet been explored in stroke patients.
Methods: The correlations among cognitive function and diffusion metrics of each subcortical fiber were
investigated in nine basal ganglia stroke patients by diffusion tensor imaging (DTI) in our study.
Results: Patient’s general cognitive and verbal working memory function correlated well with the integrity of the
left superior longitudinal fasciculus (SLF), nonverbal attention with the right inferior longitudinal fasciculus (ILF), SLF,
and frontostriatal (FS) fibers. On the other hand, nonverbal l.. View More»
