Abnormal Long-Term Episodic Memory Profiles in Multiple Sclerosis?
Author(s): Saenz Amaya, Bakchine Serge, Stepanov Igor, Omigie Diana and Ehrlé NathalieSaenz Amaya, Bakchine Serge, Stepanov Igor, Omigie Diana and Ehrlé Nathalie
Objective: Various verbal episodic memory impairments have been demonstrated in multiple sclerosis (MS), including encoding, retrieval and storage processes. Our clinical experiment suggests that a subset of MS patients may show another pattern with a distinctive evolution of performances after a 20 minutes delay (short-delay versus long-delay free recall). Methods: The current study assessed performances on the California Verbal Learning Test (CVLT) in MS with a special focus on evolution after delay to identify a subgroup of patients who may show a significant spontaneous improvement of long-delay free recall in comparison with short-delay free recall. Data from 52 MS patients were compared with those from 32 controls. Group analyses were conducted on classical scores. Individual MS performances were also analyzed, according to confidence in.. Read More»