Rocco Totaro
Rocco Totaro Multiple Sclerosis Center, Department of Neuro,
Via Vetoio, 167100 L’Aquila
Italy
Special Issue Article
Tumefactive Demyelinating Lesions in Patients with Relapsing Remitting Multiple Sclerosis Treated with Fingolimod
Author(s): Rocco Totaro, Caterina Di Carmine and Antonio CaroleiRocco Totaro, Caterina Di Carmine and Antonio Carolei
We report a case of a woman with relapsing remitting multiple sclerosis presenting with tumefactive demyelination
at disease onset and treated with natalizumab after failure of first-line drugs. Patient was shifted from natalizumab
to fingolimod treatment because of progressive multifocal leukoencephalopathy risk. Thirteen months after starting
fingolimod treatment she developed a relapse with brain MRI findings of tumefactive demyelinating lesions. We also
present a literature review on similar cases discussing a possible role of the drugs in determining brain tumefactive
lesions... View More»
