Olfa Hdiji
Tunisia
Case Report
Dementia Revealing Multiple Sclerosis
Author(s): Salma Sakka, Nouha Farhat, Amal Bouhamed, Hanen Hadj Kacem, Olfa Hdiji and Mariem Damak Chokri MhiriSalma Sakka, Nouha Farhat, Amal Bouhamed, Hanen Hadj Kacem, Olfa Hdiji and Mariem Damak Chokri Mhiri
Cognitive abnormalities are frequently observed in advanced stages of Multiple Sclerosis (MS). Their frequency increases from clinically isolated syndromes, to relapsing-remitting and secondary progressive MS. The most frequently impaired functions are information processing speed, attention and memory. Dementia is uncommon but may reveal a MS. We reported a 47-year-old woman suffering since 8 months of headache with a progressive amnesia, temporospatial disorientation and behavioral disorders. On examination, we found dementia syndrome and a frontal syndrome. Brain MRI showed a T2 hyperintensity multifocal ovoid lesions with enhancement in the periventricular white matter and in the corpus callosum. Diagnostic hypotheses were ADEM or MS. Isoelectric focusing revealed oligoclonal bands and elevated IgG index. She was treated with intravenous methylprednisolone 1 g daily for five conse.. View More»
