Mu-Hong Chen
People's Republic of China
Research Article
Transcranial Magnetic Stimulation-Derived Motor Parameters and Regional Glucose Metabolism of Motor Cortex
Author(s): Cheng-Ta Li, Chi-Hung Juan, Tung-Ping Su, Ying-Jay Liou, Mu-Hong Chen, Chih-Ming Cheng and Ying-Zu HuangCheng-Ta Li, Chi-Hung Juan, Tung-Ping Su, Ying-Jay Liou, Mu-Hong Chen, Chih-Ming Cheng and Ying-Zu Huang
Objective: Transcranial Magnetic Stimulation (TMS) has become a widely used and excellent method for examining cortical excitability abnormalities in the human system. However, the direct link between TMS measurements and its representation of regional neural brain activity is yet to be determined. We hypothesize that TMS parameter measurements of the motor cortices of both the dominant-side and non-dominant side would reflect direct correlations with their respective regional neural activities of the targeted motor cortex.
Methods: Twenty-Seven right-handed subjects were recruited under the Edinburgh Handedness Inventory. All subjects were healthy, and were exposed to excitatory and inhibitory TMS pulses from the bilateral motor cortices and brain glucose metabolism. Brain glucose metabolism was measured by 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) at rest. .. View More»
