Leigh Ann Bray
United States
Research Article
Fertility and Reproductive Health Implications of Targeted Therapeutics for Cystic Fibrosis
Author(s): Sigrid Ladores, Dheeraj Raju and Leigh Ann BraySigrid Ladores, Dheeraj Raju and Leigh Ann Bray
Aim: To explore knowledge of fertility and knowledge of the impact of cystic fibrosis (CF) on reproduction and fertility among women of childbearing age with homozygous F508del mutation, and explore these women's perceptions on fertility changes secondary to lumacaftor/ivacaftor.
Methods: This pilot had a sample of 20 women. Ten women with CF, ages 19-35 with homozygous F508del mutation, stable lung function, and English proficient were included, as well as a non-CF comparison group. Three questionnaires were administered: demographics form, Knowledge of Fertility (KF), and Knowledge of Impact of CF on Reproduction and Fertility (KICFRF). A semi-structured interview was conducted with the CF group. Interview transcripts were coded and analyzed using thematic analysis.
Results: On the KF scale, participants in b.. View More»
