Josvany Sanchez
Spain
Research Article
Sub-Albuginean Adipocyte Accumulation is Associated with Erectile Dysfunction: First Clinical Evidence and Pathophysiological Implications
Author(s): Cristian Palma, Jose Vinay, Joaquim Sarquella, Josvany Sanchez, Ariel Castro, Cesar Rojas-Cruz, Ferran Algaba, Ivan Gallegos and Ramon RodrigoCristian Palma, Jose Vinay, Joaquim Sarquella, Josvany Sanchez, Ariel Castro, Cesar Rojas-Cruz, Ferran Algaba, Ivan Gallegos and Ramon Rodrigo
The aim of this study is to determine the presence of adipocyte accumulation under penile tunica albuginea in a group of refractory erectile dysfunction patients. Nine erectile dysfunction patients (case group) and eleven potent patients with Peyronie’s disease (control group) underwent penile prosthesis implantation and curvature correction surgeries, respectively. In both groups, sub-albuginean tissue samples were taken within the operative time. Groups were compared in terms of clinical characteristics, co-morbidities and presence of sub-albuginean adipocyte accumulation. Of the nine patients in the case group, eight presented cavernous fat cell accumulation, while only one patient in the control group presented this finding (p<0.05). A significant association (p<0.05) was found between adipocyte accumulation and erectile dysfunction (OR 35 CI 95% 1.98-1727.62). A simil.. View More»
