Feijs LMG
Netherlands
Research Article
Autonomic Nervous System Functioning Associated with Epileptic Seizures: Analysis of Heart Rate Variability
Author(s): van der Kruijs SJM, Vonck KEJ, Feijs LMG, Bodde NMG, Lazeron RHC, Carrette E, Boon PAJM, Backes WH, Jansen JFA, Aldenkamp AP and Cluitmans PJMvan der Kruijs SJM, Vonck KEJ, Feijs LMG, Bodde NMG, Lazeron RHC, Carrette E, Boon PAJM, Backes WH, Jansen JFA, Aldenkamp AP and Cluitmans PJM
Objective: Little is known about the (peri-) ictal changes in autonomic nervous system activity of epileptic
seizures. Such information may be useful for seizure prediction paradigms and differential diagnosis between
epilepsy and psychogenic non-epileptic seizures (PNES). The current study investigated the peri-ictal time course of
heart rate variability (HRV) measures, which reflect autonomic nervous system functioning.
Methods: HRV measures were extracted from electrocardiography data collected during 1-7 days of videoelectroencephalography
monitoring of 17 patients with epilepsy and 20 patients with PNES. Heart rate (HR) and
HRV measures (standard deviation of average beat-to-beat intervals (SDANN), root mean square of successive
differences (RMSSD), high frequency (HF) power, low frequency (LF) power and very low frequency (VLF) po.. View More»
