Journal of Neurology & Neurophysiology

ISSN - 2155-9562

Enrico Granieri

Enrico Granieri
Department of Medical and Surgical Sciences of Communication and Behaviour,

  • Research Article
    Post-Traumatic Epilepsy: Review
    Author(s): Edward Cesnik, Ilaria Casetta and Enrico GranieriEdward Cesnik, Ilaria Casetta and Enrico Granieri

    Post traumatic epilepsy is defined by recurrent seizures secondary to brain injury following head trauma and represent the most frequent cause of epilepsy in young adults. Most post traumatic epilepsies start within two years from trauma, but in some cases may present several years after the brain injury. Severe traumatic brain injuries tend to correlate with an increased risk of developing early and late post-traumatic seizures. A cranial trauma creates a potentially epileptogenic brain damage through a number of different mechanisms. Several structural, physiological and biochemical modifications occur in a brain after a head injury that promote oxidative stress mechanisms and excitotoxic mechanisms. Current evidence shows that prophylactic use of antiepileptic drugs prevent the occurrence of early post-traumatic seizure but does not influence the incidence of post-traumatic .. View More»

    DOI: 10.4172/2155-9562.S2-009

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