Journal of Neurology & Neurophysiology

ISSN - 2155-9562

Charles W Stratton

Charles W Stratton
Department of Pathology, Microbiology and Immunology, Room 4525-TVC, The Vanderbilt Clinic, Vanderbilt University Medical Center, 1301 Medical Center Drive, Nashville, TN 37232,

  • Review Article
    A Review of Multiple Sclerosis as an Infectious Syndrome
    Author(s): Charles W StrattonCharles W Stratton

    Multiple sclerosis (MS) is a chronic neuroinflammatory disease of the central nervous system (CNS) that is generally considered to be an autoimmune myelitis of unknown etiology. Epidemiological studies suggest that infection may act as a trigger on a predisposing genetic background. A number of causative agents have been considered. This review will focus on the pathogenesis of MS and link this pathophysiology to infectious agents that have been implicated as possible co-factors. By doing so, MS will be viewed as an infectious syndrome that involves a CNS infection that results in a neurodegenerative process as well as an autoimmune disease. Early detection of infectious triggers could allow appropriate intervention and thus improved outcomes. .. Read More»
    DOI: 10.4172/2155-9562.1000400

    Abstract PDF

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