Beauvais K
France
Research Article
Terminal Latency Index (TLI) Abnormalities in Hereditary Neuropathy with
Liability to Pressure Palsies (HNPP)
Author(s): Jacquin-Piques A, Thauvin-Robinet C, Latour P, Beauvais K, Lemesle-Martin M, Soichot P and Giroud MJacquin-Piques A, Thauvin-Robinet C, Latour P, Beauvais K, Lemesle-Martin M, Soichot P and Giroud M
Introduction: The diagnosis of Hereditary Neuropathy with Liability to Pressure Palsy (HNPP) is frequently
missed or delayed because of its clinical and electrophysiological heterogeneity. Nonetheless, electrophysiological
criteria were published 15 years ago. Our aim was to highlight the Terminal Latency Index (TLI) disorders by
describing the electrophysiological characteristics in patients with HNPP.
Methods: All the consecutive patients with the clinical and genetic diagnosis of HNPP due to the 1.5Mb deletion
of PMP22 or to others mutation or deletion were included. Motor and sensory conductions were studied using
surface electrodes placed near the median, ulnar, fibular, tibial, superficial fibular and sural nerves in accordance
with standard techniques. The results were compared with our own laboratory standards.
Results: A.. View More»
