Altunel A
Mustafa Kemal Pasa Cad, Deniz Sarayı Apt 49/7, Aksaray, Fatih, Istanbul,
Turkey
Research Article
The Utility of the Hypsarrhythmia Paroxysm Index and Sleep Spindles in EEG
for Predicting Cognitive Outcomes in a Case Series of Infantile Spasms
Author(s): Altunel A, Altunel EO and Sever AAltunel A, Altunel EO and Sever A
Objectives: Among patients with West Syndrome (WS), the underlying brain dysfunction is considered to be the major determinant of cognitive outcome. However, regardless of whether the WS type is symptomatic or cryptogenic, patients with infantile spasms may have a favourable or grim prognosis. The purpose of this study was to utilize electroencephalography (EEG) to guide treatment, and to assess cognitive outcome.
Methods: We retrospectively reviewed the clinical and sleep EEG data in 16 patients who received adrenocorticotropic hormonal therapy between 2002 and 2014. The hypsarrhythmia paroxysm index (HPI), the frequency or duration of hypsarrhythmia paroxysms in non-rapid eye movement (NREM) sleep, and sleep spindles were evaluated in groups constituted according to etiology.
Results: Cryptogenic patients whose onset.. View More»
