Chong-Woo Chu*, Seong-Geun Kim and Jeong-Hee Kang
Background
Patients with multiple liver metastases from breast cancer are typically considered ineligible for surgical treatment due to the extent of disease. However, aggressive surgical strategies may offer long-term survival benefits in selected cases. This case series aims to illustrate the potential role of tailored surgical interventions in patients with extensive liver metastases.
Methods
We present two cases of female patients diagnosed with multiple bilobar liver metastases from breast cancer. The first patient, treated in 2020, had 20 bilobar liver metastases and underwent combined resection and radiofrequency ablation (RFA). The second patient, treated in 2023, had 18 bilobar metastases and underwent a two-stage hepatectomy using the associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) procedure.
Results
Both patients achieved complete resection of all visible liver metastases through the respective surgical approaches. Follow-up assessments revealed no evidence of disease recurrence in either patient.
Conclusion
These cases demonstrate that, in carefully selected patients, aggressive and individualized surgical strategies may enable complete resection and provide the possibility of long-term survival, even in the setting of extensive liver metastases from breast cancer.