Chong-Woo Chu, Seong-Geun Kim, Jeong-Hee Kang
Background
Patients with multiple liver metastases from breast cancer are
typically considered ineligible for surgical treatment due to the
extent of disease. However, aggressive surgical strategies may
offer long-term survival benefits in selected cases. This case
series aims to illustrate the potential role of tailored surgical
interventions in patients with extensive liver metastases.
Methods
We present two cases of female patients diagnosed with multiple
bilobar liver metastases from breast cancer. The first patient,
treated in 2020, had 20 bilobar liver metastases and underwent
combined resection and radiofrequency ablation (RFA). The second
patient, treated in 2023, had 18 bilobar metastases and underwent
a two-stage hepatectomy using the associating liver partition and
portal vein ligation for staged hepatectomy (ALPPS) procedure.
Results
Both patients achieved complete resection of all visible liver
metastases through the respective surgical approaches. Followup
assessments revealed no evidence of disease recurrence in
either patient.
Conclusion
These cases demonstrate that, in carefully selected patients,
aggressive and individualized surgical strategies may enable
complete resection and provide the possibility of long-term
survival, even in the setting of extensive liver metastases from
breast cancer.