International Journal of Collaborative Research on Internal Medicine & Public Health

ISSN - 1840-4529

Abstract

Renal Changes in Length and Parenchymal Thickness in Diabetic and Hypertensive Patients with Normal eGFR & Serum Creatinine Using Ultrasonography

Adil A Mansour*, Hossam Gasmalseed, Mohamed Abdalla Eltahir and Mohamed Elhag Osman

This study was proposed to measure the renal length and parenchymal thickness in Adult diabetic and hypertensive patients with normal eGFR and serum creatinine using ultrasonography in order to detect early reduction in renal length and parenchymal thickness in Sudanese population. Ultrasonographic kidney measurements were performed on 66 adult patients with known diabetes and hypertension with different duration of the disease. The impact of age, gender, site (left and right side) and height was statistically analyzed. Patients with abnormal eGFR, serum creatinine or any renal disease were excluded. This study was included 27 males and 39 females with age ranging from 26-75 years. The study was divided into three groups; Group ''A'' includes 35 patients with diabetes and hypertension (DM & HTN), group ''B'' includes 15 patients with diabetes only (DM) and group ''C'' includes 16 patients with hypertension only (HTN). The duration of the (DM and HTN) ranging from 5-30 years.

The mean of right renal lengths were 10.36 ± 0.988, 10.38 ± 1.49421 and 10.20 ± 0.71 cm for DM & HTN, DM and HTN respectively. The mean of left renal lengths were 10.84 ± 0.111 cm, 10.71 ± 1.15 cm and 10.33 ± 0.91 cm for DM & HTN, DM and HTN respectively. No significant difference noted in the right or left renal length. The mean of right renal parenchymal thicknesses were (1.52 ± 0.41 cm, 1.76 ± 0.26 cm and 1.45 ± 0.27 cm for DM & HTN, DM and HTN respectively. The mean of left renal parenchymal thicknesses were 1.90 ± 0.74 cm, 1.9 ± 0.28 cm and 1.75 ± 0.35 cm for DM & HTN, DM and HTN respectively. There is significant difference in right parenchymal thickness at p=0.03.

The numbers of patients with small, normal and large right renal length were 5, 57 and 4 respectively. The numbers of patients with small, normal and large left renal length were 1, 57 and 8 cases respectively. No significant difference among the three groups DM & HTN, DM and HTN.

The numbers of patients with thin, normal and thick right renal parenchymal thicknesses 5, 57 and 4 respectively. The numbers of patients with small, normal and large left renal length were 1, 57 and 8 cases respectively. No significant difference among the three groups DM & HTN, DM and HTN.

These results were correlated with age, gender, site, and height which showed that there is no significant difference between right and left renal length. The significant difference of age was found only in left parenchymal thicknesses at p=0.0. No significant difference of gender or height was noted in renal lengths or parenchymal thicknesses.

The study concluded that the right parenchymal thickness was affected with disease DM&HTN, DM and HTN and the left parenchymal thickness was affected with age.

 
Top