Nishi Saxena, Ameeta Argal
Diabetes causes hyperglycemia. It affects vital organs. Herbal plants in combination have great potential for antidiabetic activity. Therefore a herbal suspension containing alcoholic extract of Annona squamosa leaves, Aegele marmelos leaves and Azadirachta indica leaves was prepared and evaluated for its organoleptic characteristics, physicochemical parameters and antidiabetic activity. The suspension was free flowing and easily dispersible. The organoleptic and physicochemical properties were satisfactory. Antidiabetic activity was studied in streptozotocin induced diabetic rats. The standard drug used was Glibenclamide 600 μg/kg. Herbal suspension at both the doses of 25 and 50μg/ml was having significant activity. The weight gain and decrease in blood glucose level was less than that of standard drug. Thus the prepared oral herbal suspension is safe for use with promising antidiabetic activity.
